First consultation and data integrationInitial summary of the genetic profile by area
Interpret the attached NutriGPT genetic file with the Panel Guide. Give me a table by area with each variant, its number of copies and its reading, mark the variants with no data, and summarise in five points which guidance from their NutriGPT genetic profile should most influence the eating plan.
PC-01
First consultation and data integrationCross the genetic profile with the dietary history
I attach the client's NutriGPT genetic file and a summary of their dietary history: [habits, timings, foods they avoid, previous diets]. Identify where their current habits already fit the guidance from their NutriGPT genetic profile and where there is most room for improvement, and rank those changes by expected impact and ease.
PC-02
Vitamins and mineralsNatural folate according to MTHFR
According to their NutriGPT genetic file, my client has [n] copies of the reference allele at MTHFR rs1801133 (C677T) and [n] at MTHFR rs1801131 (A1298C). Design a week of menus that reaches the reference intake of folate with natural foods (leafy greens, pulses, citrus, nuts), with the approximate daily contribution and cooking techniques that reduce losses.
VM-01
Vitamins and mineralsFolate intake versus MTHFR
With this 3-day food record [paste], estimate folate intake and compare it with the reference intake. Taking into account the MTHFR rs1801133 and rs1801131 readings in their NutriGPT genetic file, suggest five simple swaps that improve it without changing their style of eating.
VM-02
Dietary fatsPreferred type of fat according to the genetic profile
With the variants in the “Response to dietary fats” area of their NutriGPT genetic file, explain which type of fat should predominate in the client's diet and translate it into weekly portions of olive oil, nuts, oily fish and dairy.
GR-01
Dietary fatsSaturated fat according to APOA2 and FABP2
Analyse this 3-day record [paste] and identify the main sources of saturated fat. With the APOA2 rs5082 and FABP2 rs1799883 readings in their NutriGPT genetic file, suggest specific swaps that keep dishes they enjoy.
GR-02
Dietary fatsA Mediterranean pattern personalised by the genetic profile
With ADIPOQ rs17300539 and PPARG rs1801282 from their NutriGPT genetic file, adapt the Mediterranean pattern to their habits [habits] and check their current adherence with the 14 items of the MEDAS questionnaire (PREDIMED).
GR-03
Carbohydrates and chrononutritionType of carbohydrate according to the genetic profile
With the variants in the “Carbohydrates and meal timing” area of their NutriGPT genetic file, explain which carbohydrates to prioritise (wholegrains, pulses, whole fruit) and which to moderate, and how to combine them with protein and fibre at each meal.
CH-01
Carbohydrates and chrononutritionDinner timing according to MTNR1B and CLOCK
According to MTNR1B rs10830963 and CLOCK rs1801260 in their NutriGPT genetic file, and knowing that they have dinner at [time] and go to bed at [time], propose a realistic dinner schedule and a light model dinner for each weekday.
CH-02
Carbohydrates and chrononutritionCarbohydrate distribution according to MTNR1B and IRS1
With MTNR1B rs10830963 and IRS1 rs2943641 from their NutriGPT genetic file, distribute the day's carbohydrates between breakfast, lunch, afternoon snack and dinner for their routine [routine] and explain why.
CH-03
Appetite, satiety and body compositionSatiety strategies according to the genetic profile
With the variants in the “Appetite and satiety” area of their NutriGPT genetic file, design ten specific satiety strategies for this client (volume, protein, fibre, eating speed, meal structure) and how to measure whether they work.
AS-01
Appetite, satiety and body compositionProtein distribution according to LEPR
According to LEPR rs1137101 in their NutriGPT genetic file and their goal [goal], distribute daily protein across meals (paying attention to breakfast) and suggest plant and animal sources for each.
AS-02
Appetite, satiety and body compositionEnergy density according to FTO and MC4R
With FTO rs9939609 and MC4R rs17782313 from their NutriGPT genetic file, reformulate five of the client's usual dishes [dishes] to reduce their energy density without losing volume or flavour.
AS-03
Coffee, taste and food preferencesCoffee: amount and timing according to CYP1A2
With CYP1A2 rs762551 and rs2069514 from their NutriGPT genetic file and their current intake [cups and times], propose an adapted coffee routine (amount and cut-off time) and afternoon alternatives.
CP-01
Coffee, taste and food preferencesHidden caffeine according to CYP1A2
With the CYP1A2 rs762551 reading in their NutriGPT genetic file, list less obvious sources of caffeine (tea, cola drinks, energy drinks, chocolate, pre-workouts) and estimate the total caffeine in their day from their record [paste].
CP-02
Coffee, taste and food preferencesCoffee and sleep according to CYP1A2 and CLOCK
According to CYP1A2 rs762551 and CLOCK rs1801260 in their NutriGPT genetic file and their sleep data [hours, quality or wearable data], assess whether coffee timing may be affecting their rest and propose a two-week trial.
CP-03
Inflammation and antioxidant defenceAnti-inflammatory pattern according to the genetic profile
With the variants in the “Inflammation and antioxidant defence” area of their NutriGPT genetic file, design an anti-inflammatory eating pattern based on the Mediterranean model, with a week of menus and the shopping list.
IA-01
Inflammation and antioxidant defencePolyphenols in the diet according to the genetic profile
With the readings in the “Inflammation and antioxidant defence” area of their NutriGPT genetic file, suggest how to increase polyphenols (berries, pure cocoa, tea, spices, extra virgin olive oil, pulses) at each meal of the day.
IA-02
Inflammation and antioxidant defenceCruciferous vegetables according to NQO1 and NFE2L2
With NQO1 rs1800566 and NFE2L2 rs6721961 from their NutriGPT genetic file, plan how to include cruciferous vegetables four times a week and explain how to prepare them (chop and rest, short cooking) to preserve sulforaphane.
IA-03
Salt and potassiumReducing salt according to AGT
With the AGT rs699 reading in their NutriGPT genetic file, propose a plan to reduce salt at home (spices, acids, cooking techniques) and a gradual reduction schedule so the palate adapts.
SP-01
Salt and potassiumHidden salt in their shopping according to AGT
According to AGT rs699 in their NutriGPT genetic file, review this record or shopping list [paste], identify the main sources of hidden salt (bread, cured meats, cheeses, sauces, ready meals) and suggest alternatives.
SP-02
Salt and potassiumPotassium in the diet according to AGT
With AGT rs699 from their NutriGPT genetic file, design a potassium-rich model day (vegetables, fruit, pulses, nuts) and estimate its contribution against the recommendation.
SP-03
Exercise, recovery and restType of training according to ACTN3 and ACE
With ACTN3 rs1815739 and ACE rs4343 from their NutriGPT genetic file, describe which type of training the client seems to adapt to best and how to combine strength and endurance in their week [availability], making clear that every profile benefits from both.
ED-01
Exercise, recovery and restPeri-workout nutrition according to PPARGC1A
According to PPARGC1A rs8192678 in their NutriGPT genetic file and their training schedule [schedule], suggest what to eat before and after training (carbohydrates, protein, hydration) on training and rest days.
ED-02
Exercise, recovery and restTendons and ligaments according to COL1A1 and COL5A1
With COL1A1 rs1800012 and COL5A1 rs12722 from their NutriGPT genetic file, suggest tendon and ligament care habits (warm-up, progressive loading, mobility) and their nutritional support (sufficient protein, vitamin C with meals), and recommend that an exercise professional validates it.
ED-03
Situations and eating patternsA vegan diet planned with the genetic profile
My client is vegan. With the readings in the “Vitamins and minerals” area of their NutriGPT genetic file, review their critical nutrients (B12, omega-3, vitamin A, vitamin D, calcium, iodine, iron, zinc) and design a complete week of menus, noting what they should discuss with their doctor.
SV-01
Situations and eating patternsActive older adults and the genetic profile
My client is [age] years old and independent. With the vitamin D, vitamin B12 and exercise variants in their NutriGPT genetic file, propose a plan that looks after muscle mass, hydration and appetite, adapted to the way they cook.
SV-02
Situations and eating patternsShift work and the chronobiological profile
My client works rotating shifts [shifts]. With MTNR1B rs10830963, CLOCK rs1801260 and CYP1A2 rs762551 from their NutriGPT genetic file, propose how to organise meals, coffee and rest on each type of shift.
SV-03
Communication, adherence and follow-upExplain the genetic profile in 300 words
Write an explanation of about 300 words for the client on what their NutriGPT genetic profile means for their diet and habits, in a friendly tone, without alarmism and making clear that it is not a diagnosis.
CS-01
Communication, adherence and follow-upOne-page summary of the genetic profile for the client
With the priority guidance from their NutriGPT genetic profile, create a one-page sheet for the client with their three goals for the month, five meal ideas and a daily adherence table, with no technical genetic terms.
CS-02
Communication, adherence and follow-upMotivational interviewing supported by the genetic profile
With their NutriGPT genetic profile and what they have told me about their barriers [barriers], suggest open questions and motivational-interviewing phrases for the next session that use their results as a lever for change.
CS-03